抗菌肽作为饲料添加剂的研究进展

Journal of Tianjin Agricultural University ›› 2013, Vol. 20 ›› Issue (4): 48-51.

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Research Progress of Antimicrobial Peptides as Feed Additive

HU Ye, MA Ji-fei, ZHAO Rui-li

Department of Animal Science, Tianjin Agricultural University, Tianjin 300384, China

Received:2013-04-07 Published:2019-10-21

Abstract

Abstract: Antimicrobial peptides (AMPs) are important bioactive polypeptides induced by the innate system of organisms. These peptides are of broad-spectrum activities against a wide range of microorganisms including Gram-positive and Gram-negative bacteria, and can inhibit fungi, some enveloped viruses, parasites, and the growth of some tumor cells. AMPs have unique antibacterial mechanisms and may become a new alternative to antibiotics as well as a kind of green feed additive of high efficiency and high quality. In this review, it is discussed the classification, function, mechanism, and the application and development prospect of AMPs in the animal production.

Key words: antimicrobial peptide, classification and function, mechanism

CLC Number:

S816.73

HU Ye, MA Ji-fei, ZHAO Rui-li. Research Progress of Antimicrobial Peptides as Feed Additive[J]. Journal of Tianjin Agricultural University, 2013, 20(4): 48-51.

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References

[1] Hancock R E.Peptide antibiotics[J]. Lancet, 1997, 349(9049):418-422.
[2] Andreu D, Rivas L.Animal antimicrobial peptides: an overview[J]. Biopolymers,1998,47:415-433.
[3] Vizioli J, Salzet M.Antimicrobial peptides from animal: focus on invertebrates[J].Trends Pharmacological Sciences,2002,23(11):494-496.
[4] Koczulla A R,Bals R.Antimicrobial peptides:current status and therapeutic potential[J]. Drugs,2003,63(4): 389-406.
[5] Vega L A,Caparon M G.Cationic antimicrobial peptides disrupt the streptococcus pyogenes ExPortal[J]. Molecular Microbiology,2012,85(6):1119-1132.
[6] Dagan A,Efron L,Gaidukov L,et al.In vitro antiplasmodium effects of dermaseptin S4 derivatives[J]. Antimicrob Agents Chemother,2002,46(4):1059-1066.
[7] Bulet P,Stocklin R.Insect Antimicrobial peptides: structures, properties and gene regulation[J]. Protein and Peptide Letters,2005,1(12):3-11.
[8] Albiol M C,Castilla V.Antiviral activity of antimicrobial cationic peptides against Junin virus and herpes simplex virus[J]. Int J Antimicrob Agent,2004,23(4):382-389.
[9] Suttmann H,Retz M,Paulsen F,et al.Antimicrobial peptides of the cecropin-family show potent antitumor activity against bladder cancer cells[J]. BMC Urology, 2008,8:5-11.
[10] Lu J,Chen Z W.Isolation, characterization and anti- cancer activity of SK84, a novel glycine-rich antimicrobial peptide from Drosophila virilis[J]. Peptides,2010,31(1):44-50.
[11] Jenssen H,Hamill P,Hancock R E.Peptide antimicrobial agents[J]. Clinical Microbiology Reviews,2006,19(3): 491-511.
[12] 朱嘉明,刘飞鹏,李月琴,等. 天蚕抗菌素肤A与蜂毒素杂合肽基因的合成及在大肠杆菌中的克隆与表达[J]. 遗传,2002,24(1):31-34.
[13] 刘先凯,赵彤言. 昆虫抗菌肽研究进展[J]. 寄生虫与医学昆虫学报,2001,8(2):115-121.
[14] 姚朔影,李超能,谢浩良,等. 抗菌肽杀菌机理与杀菌特性研究[J]. 中国食品添加剂,2003(4):11.
[15] Yeaman M R,Yount Nannette Y.Mechanisms of antimicrobial peptide action and resistance[J]. Pharmacological Reviews,2003(55):27-55.
[16] 江丽娜, 赵瑞利. 抗菌肽的研究进展[C]//首届中国兽药大会——兽医生物制品学、兽医微生物学学术论坛论文集. 天津:兽医生物制品学分会、兽医徽生物学分会,2008:94-97.
[17] Aarbiou J,Tjabringa G S,Verhoosel R M,et al.Mechanisms of cell death induced by the neutrophil antimicrobial peptides α-defensins and LL-37[J]. Inflamm Res,2006,55(3):119-127 .
[18] 马卫明,佘锐萍,靳红,等. 猪小肠抗菌肽的抗菌作用研究[J]. 中国兽医杂志,2005,41(1):3-7.
[19] 陈晓生,张辉华,周庆国,等. 抗菌肽对肉鸭雏鸭期肠道主要微生物菌落的影响[J]. 兽药与饲料添加剂,2006,11(4):1-2.
[20] 温刘发,何丹林,张常明,等. 抗菌肽酵母制剂作为饲料添加剂的应用前景[J]. 中国饲料,2001(23):22-23.
[21] 汪以真. 猪乳铁蛋白基因克隆、表达及产物对断奶仔猪生长、免疫和抗菌肽基因表达影响的研究[D]. 杭州:浙江大学,2004.
[22] Tang Z R,Yin Y L,Zhang Y M,et al.Effects of dietary supplementation with an expressed fusion peptide bovine lactoferricin-lactoferrampin on performance,immune function and intestinal mucosal morphology in piglets weaned at age 21 d[J]. British Journal of Nutrition,2009,101:998-1005.
[23] 郭丽君,牛淑玲,马倩,等. 抗菌肽制剂对芦花鸡胸肌肉质性状、游离氨基酸及微量元素含量的影响[J]. 动物营养学报,2012,24(4):1-7.
[24] Perron G G,Zasloff M,Bell G.Experimental evolution of resistance to an antimicrobial peptide[J]. Proceedings of the Royal Society B: Biological Sciences,2006,273(1583):251-256.
[25] Fuente-Núñez C D,Mertens Jan,Smit J,et al. The bacterial surface layer provides protection against antimicrobial peptides[J]. Appl Environ Microbiol,2012,78:5452-5456.

Research Progress of Antimicrobial Peptides as Feed Additive

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