Abstract: The purpose of this study was to evaluate the effects of compound lactic acid bacteria, LP（Lactobacillus plantarum）combined with LR（Lactobacillus reuteri）as feed additive on the prevention of bacterial diarrhea and growth performance of weaned piglets. Twelve 28-day-old weaned piglets with an average body weight of（6.77±1.30）kg were divided into two groups with 6 replicates per group and 1 pig per replicate. The piglets in the control group were fed with basic diet from 0 to 28 days; 1×10⁹ CFU/kg compound lactic acid bacteria preparation were added to the basic diet of piglets in the experimental group for 0~14 days and 5×10⁸ CFU/kg compound lactic acid bacteria preparation for 15~28 days. The experiment lasted for 28 days. Body weight was measured weekly and feed intake was checked every day. The incidence of diarrhea was assessed daily by stool score and diarrhea index was calculated. Fecal samples were collected at 14th and 28th days for the counting of lactic acid bacteria and coliform bacteria. The results showed as follows: compared with the control group, the ADG, ADFI and FCR of weaned piglets supplemented with compound lactic acid bacteria preparation had a trend of improvement（P>0.05）, the number of intestinal LAB（lactic acid bacteria）was significantly increased（P<0.05）and intestinal coliform bacteria was significantly decreased（P<0.05）. The ratio of intestinal LAB to coliform bacteria was significantly increased（P<0.05）. In addition, fecal consistency score, diarrhea incidence and diarrhea index were significantly decreased（P<0.05）after weaned piglets were fed diets supplemented with compound lactic acid bacteria preparation. The fecal consistency score, diarrhea incidence and diarrhea index of weaned piglets decreased significantly when LP and LR were added 5×10⁸ CFU/kg respectively in the basic diet.

Key words: compound lactic acid bacteria preparation, weaned piglets, growth performance, bacterial diarrhea, correlation