苦瓜皂苷与南瓜多糖或苦荞黄酮联合作用对高脂血症大鼠糖脂代谢的影响

doi:10.19640/j.cnki.jtau.2021.02.011

Journal of Tianjin Agricultural University ›› 2021, Vol. 28 ›› Issue (2): 51-55.doi: 10.19640/j.cnki.jtau.2021.02.011

• Researches and Scientific Notes • Previous Articles Next Articles

Effect of bitter melon saponins with pumpkin polysaccharides or buckwheat flavones on glucose and lipid metabolism in hyperlipidemia rats

Guo Yi¹, Li Yiteng¹, Wu Haiqing^1,2, Wang Bujiang^1,2, Xiao Ping^1,2,*, Liu Jinfu^1,2,*

1. College of Food Science and Bioengineering, Tianjin Agricultural University, Tianjin 300392, China;
2. Tianjin Engineering and Technology Research Center of Agricultural Products Processing, Tianjin 300392, China

Received:2020-07-07 Published:2021-07-26

Abstract

Abstract: The effects of bitter melon (Momordica charantia) saponins, pumpkin (Cucurbita moschata) polysaccharides and buckwheat (Fagopyrum tataricum) flavones on glucose and lipid metabolism in hyperlipidemic rats were studied by single- dimensional statistical analysis combined with principal component analysis. The results showed that combined bitter melon saponins and pumpkin polysaccharide significantly improved levels of TC, FFA, CRE and LP compared with that of individual extracts (P<0.05). Bitter melon saponin and buckwheat flavones improved effect of TC, CRE and FFA significantly better than that of single component (P<0.05). PCA analysis also confirmed that the combined effect of active ingredients produced more improvement of glucose and lipid metabolism in hyperlipidemic rats by acting on different target pathways.

Key words: bitter melon (Momordica charantia) saponins, pumpkin (Cucurbita moschata) polysaccharides, buckwheat (Fagopyrum tataricum) flavones, hyperlipidemia, glucose and lipid metabolism, combined effect

CLC Number:

TS255.1

Guo Yi, Li Yiteng, Wu Haiqing, Wang Bujiang, Xiao Ping, Liu Jinfu. Effect of bitter melon saponins with pumpkin polysaccharides or buckwheat flavones on glucose and lipid metabolism in hyperlipidemia rats[J]. Journal of Tianjin Agricultural University, 2021, 28(2): 51-55.

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Effect of bitter melon saponins with pumpkin polysaccharides or buckwheat flavones on glucose and lipid metabolism in hyperlipidemia rats

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