Journal of Tianjin Agricultural University ›› 2016, Vol. 23 ›› Issue (1): 62-65.

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Research Progress in Listeria Phage Endolysins

LIU Shan-na, FAN Zhi-hua, SUN Xi, FU Rong-xia, WU Hai-qing   

  1. Tianjin Engineering and Technology Research Center of Agricultural Products Processing, College of Food Science and Bioengineering, Tianjin Agricultural University, Tianjin 300384, China
  • Received:2015-08-18 Online:2016-03-20 Published:2019-10-14

Abstract: Listeria monocytogenes is an important genus of food-borne pathogens. It may transmit into human body through contaminated food and cause food safety issue. Bacteriophages are effective means for Listeria bio-control, which can specifically recognize bacterial cells and lead to bacterial lysis. The key to antibacterial activities of bacteriophages relies on double stranded DNA-encoded endolysins, the murein enzymes which degrade host cell wall and result in release of phage progeny to the extracellular environment at the end of the phage lytic multiplication cycle. This article reviews the category of Listeria phage endolysins, the mechanism and structural feature of them, and discusses the application area and direction for development of endolysins in the future.

Key words: Listeria, bacteriophage, endolysin, research progress

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