[1] Duan Rui-ling, Li Qing-xiang,Li Yu-he.Summary of image edge detection[J]. Optical Technique,2005,31(3):415-419. [2] Wang Xun,Jin Jiang-qiu.An edge detection algorithm based on improved CANNY operator[J]. Seventh International Conference on Intelligent Systems Design and Application,2007,20(2):623-628. [3] Zhao Yu-qia,Gui Wei-hua,Chen Zheng-cheng,et al.Medical images edge detection based on mathematical morphologoy[C]//IEEE-EMBS. Proceeding of the 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference. Shanghai: Shanghai Jiaotong University,2005:6492-6495. [4] Yan Wen-zhong,Shen Shu-qun.An edge detection method for chromosome images[C]. IEEE-EMBS. The 2nd International Conference of Bioinformatics and Biomedical Engineering. Suzhou: Suzhou Institute of Biomedical Engineering and Technology,CAS,China,2008:2390-2392. [5] Rafael C Gonzalez,Richard E Woods.Digital Image Processing[M]. New Jersey:Prentice-Hall Inc,2002:1058-1083.