牛磺酸对不同饲养方式蛋鸡肾脏功能、抗氧化能力和细胞因子水平的影响

天津农学院学报 ›› 2014, Vol. 21 ›› Issue (1): 9-14.

牛磺酸对不同饲养方式蛋鸡肾脏功能、抗氧化能力和细胞因子水平的影响

张金秋¹, 马子力^2,3, 韩立秋², 卢宇¹, 苗晋锋², 侯继波^{1,通信作者}

1. 江苏省农业科学院国家兽用生物制品工程技术研究中心南京 210014;
2. 南京农业大学动物医学院,南京 210095;
3. 东阳市畜牧兽医局,浙江东阳 322100

收稿日期:2013-11-23 发布日期:2019-10-21
通讯作者: 侯继波（1960-）,男,山东德州人,研究员,博士,主要从事兽用生物制品工程技术。E-mail：houjiboccvv@163.com。
作者简介:张金秋（1982-）,女,河南南阳人,助理研究员,博士在读,主要从事天然免疫与畜禽健康方向研究。E-mail：jqzh03@126.com。
基金资助:
江苏省农业科技自主创新资金项目“水包油乳剂的免疫增强机制研究”（CX（12）5064）及“线粒体MAVS蛋白在抗H3N2亚型猪流感病毒感染过程中的作用”（CX（13）5037）; 公益性行业（农业）科研专项经费项目“畜禽福利养殖关键技术体系研究与示范”（201003011）

Influence of Dietary Taurine on Renal Functions, Anti-oxidation Activity and Cytokines Level in Laying Hens with Different Rearing Patterns

ZHANG Jin-qiu¹, MA Zi-li^2,3, HAN Li-qiu², LU Yu¹, MIAO Jin-feng², HOU Ji-bo^{1,Corresponding Author}

1. National Research Center for Veterinary Vaccine Engineering and Technology of China, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China;
2. College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China;
3. Animal Husbandry and Veterinary Bureau of Dongyang, Dongyang 322100, Zhejiang Province, China

Received:2013-11-23 Published:2019-10-21

摘要/Abstract

摘要： 选择生长发育正常的绿壳蛋鸡15 000只,随机分成笼养高密度组、笼养低密度组和散养组,每组又分为对照组和实验组,2 500只/组。对照组饲喂正常日粮,实验组饲喂添加0.1%的牛磺酸日粮。在实验期第90天,每组随机选取10只采集血液和肾脏,进行肾脏形态和相关生化指标检测。结果显示：饲养方式和日粮中添加0.1%牛磺酸对血清中SCr和UA含量没有显著影响（P>0.05）;笼养蛋鸡血清BUN含量无论在高密度组还是低密度组均显著高于散养组（P<0.05）。iNOs活性、TNF-α、IFN-γ、IL-4和IL-10等和炎症免疫相关的细胞因子水平在各饲养模式及处理间均无显著差异。饲养方式对肾脏组织中MDA含量、SOD和T-AOC活性无显著影响。散养组肾脏T-AOC活性显著高于笼养高密度组（P<0.05）;日粮中添加0.1%牛磺酸可以显著升高散养组和笼养高密度组肾脏T-AOC活性（P<0.05）。结果表明,散养、降低饲养密度和日粮中添加牛磺酸可以提高肾脏组织抗氧化水平,调控机体的代谢,改善饲养应激造成的肾脏组织损伤,进而提高蛋鸡的健康水平。

关键词: 牛磺酸, 蛋鸡, 饲养方式, 肾脏

Abstract: 15 000 green-shell laying hens（148 day-old）were randomly assigned into a free range group, and 2 caged groups with low-density and high-density housing, respectively. Each group was further divided into the control（C）and taurine treatment（T）groups. All the test subjects were fed the same basic diet except that the T groups was supplemented with 0.1% taurine. After 90 days, serum, kidneys were aseptically collected. The results show that there was no significant change of serum concentrations of SCr and UA between different groups（P>0.05）. Compared with free range group, serum BUN concentrations were higher both in high-density group and low-density group（P<0.05）. No significant difference was observed on iNOs activities and TNF-α, IFN-γ, IL-4, IL-10 concentrations in different groups. There was no significant change of MDA content, SOD and T-AOC activity in kidney tissue under different rearing patterns（P>0.05）. Compared with high-density group, the T-AOC levels in free range group increased obviously（P<0.05）. The T-AOC levels of free range group and caged groups with high-density housing with 0.1% taurine increased significantly（P<0.05）. The data indicate that free range, reduced housing density and taurine could influence anti-oxidation level, regulate metabolism and protect the normal function of the kidney and thus enhance the health of laying hens.

Key words: taurine, laying hen, rearing pattern, kidney

中图分类号:

S831.5

张金秋, 马子力, 韩立秋, 卢宇, 苗晋锋, 侯继波. 牛磺酸对不同饲养方式蛋鸡肾脏功能、抗氧化能力和细胞因子水平的影响[J]. 天津农学院学报, 2014, 21(1): 9-14.

ZHANG Jin-qiu, MA Zi-li, HAN Li-qiu, LU Yu, MIAO Jin-feng, HOU Ji-bo. Influence of Dietary Taurine on Renal Functions, Anti-oxidation Activity and Cytokines Level in Laying Hens with Different Rearing Patterns[J]. Journal of Tianjin Agricultural University, 2014, 21(1): 9-14.

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