部分水产动物性别决定基因的研究进展

天津农学院学报 ›› 2013, Vol. 20 ›› Issue (4): 45-47.

部分水产动物性别决定基因的研究进展

崔培¹, 金诗语¹, 李建¹, 陈师¹, 王雪², 李永仁^{1,通信作者}

1. 天津农学院天津市水产生态及养殖重点实验室,天津 300384;
2. 大连海洋大学海洋生物资源可持续利用重点实验室,辽宁大连 116023

收稿日期:2012-11-18 发布日期:2019-10-21
通讯作者: 李永仁（1978-）,男,天津市人,讲师,硕士,主要从事水产动物的遗传育种研究。E-mail：lyr1018@163.com。
作者简介:崔培（1985-）,女,天津市人,助理实验师,硕士,主要从事水产动物研究。E-mail：icp7410@hotmail.com。
基金资助:
天津市高等学校发展基金计划项目“菲律宾蛤仔三倍体育种研究”（20110623）; 大连市科学技术基金项目“利用分子标记辅助选择法快速建立中间球海胆优良生长家系的研究”（2007J23JH024）

Research Progress of Sex-Determining Genes in Some Aquatic Animals

CUI Pei¹, JIN Shi-yu¹, LI Jian¹, CHEN Shi¹, WANG Xue², LI Yong-ren^{1,Corresponding Author}

1. Key Laboratory of Aqua-ecology and Aquaculture of Tianjin, Tianjin Agricultural University, Tianjin 300384, China;
2. Key Laboratory of Marine Bio-resources Sustainable Utilization in Liaoning Province, Dalian Ocean University, Dalian 116023, Liaoning Province, China

Received:2012-11-18 Published:2019-10-21

摘要/Abstract

摘要： 继在哺乳动物中发现了性别决定基因SRY后,相关学者还发现了诸如性别连锁基因、芳香化酶基因、锌指结构基因、H-Y抗原、Sox、DMRT1、DMY等许多与性别控制和性腺发育相关的基因,为进一步阐明鱼类性别决定机制提供了基础和手段,但仍存在一些问题有待探索。本文概述了近年来部分水产动物性别决定基因方面的研究动态和进展,并对其应用前景做了简述,以期为系统研究鱼类性别决定机制提供参考。

关键词: 水产动物, 性别决定基因, 研究前景

Abstract: Since the discovery of the sex-determining gene SRY, a number of genes have been identified which are involved with sex determination and gonads development (sex-linked gene, aromatases gene, ZFY, H-Y antigen, Sox, DMRT1, DMY). These findings lay a foundation and provide potential tools for further studies aiming at elucidation of the mechanism of sex determination, but there are still some questions that need further researches. In this review, the progress in the recent decades on sex-determining related genes of aquatic animals was summarized and the application prospects of these results were also discussed. This paper is expected to provide some references for systematic studies on mechanism of aquatic animal sex determination.

Key words: aquatic animal, sex-determining gene, research prospect

中图分类号:

Q343.1

崔培, 金诗语, 李建, 陈师, 王雪, 李永仁. 部分水产动物性别决定基因的研究进展[J]. 天津农学院学报, 2013, 20(4): 45-47.

CUI Pei, JIN Shi-yu, LI Jian, CHEN Shi, WANG Xue, LI Yong-ren. Research Progress of Sex-Determining Genes in Some Aquatic Animals[J]. Journal of Tianjin Agricultural University, 2013, 20(4): 45-47.

导出引用管理器 EndNote|Reference Manager|ProCite|BibTeX|RefWorks

链接本文: http://xuebao.tjau.edu.cn/CN/

http://xuebao.tjau.edu.cn/CN/Y2013/V20/I4/45

参考文献

[1] Sinclair A H,Berta P,Palmer M S,et al.A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif[J]. Nature,1990,346(6281):240-244.
[2] Soullier S,Jay P,Poulat F,et al.Diversification pattern of the HMG and Sox family members during evolution[J]. J Mol Evol,1999,48(5):517-527.
[3] Herpin A,Braasch I,Kraeussling M,et al.Transcriptional rewiring of the sex determining DMRT1 gene duplicate by transposable elements[J]. Plos Genetics,2010,6(2):e1000844.
[4] 李虎. 半滑舌鳎性别决定机制、养殖群体性比及雌雄形态差异研究[D]. 上海:上海海洋大学,2012.
[5] 江山. 金鱼雌核发育及其性别分化相关基因的表达[D]. 上海:上海海洋大学,2012.
[6] 姚延丹,龙华,陈建武,等. 鱼类性别决定及其研究方法进展[J]. 上海海洋大学学报,2009,18(1):94-100.
[7] Wachtel S,Demas S,Tiersch T,et al.Bkm satellite DNA and ZFY in the coral reef fish Anthias squamipinnis[J] . Genome,1991,34(3):612-617.
[8] 周荣家,余其兴,程汉华. SRY盒基因在斑马鱼和胡子鲶中的保守性分析[J]. 遗传,1996,18(1):1-3.
[9] 周荣家,余其兴,程汉华,等. PCR扩增黄鳝和刺鳅SRY盒基因[J]. 科学通报,1996,47(7):640-642.
[10] Yao B,Zhou L,Gui J F,et al.Differential expression and dynamic changes of SOX3 during gametogenesis and sex reversal in protogynous hermaphroditic fish[J]. Journal of Experimental Zoology Part A:Ecological Genetics and Physiology,2007,4(307A):207-219.
[11] 汪锐,程汉华,郭一清,等. 脊椎动物Sox基因家族的系统发生分析[J]. 遗传学报,2002,29(11):990-994.
[12] Fukads S,Tanaka M,Iwaya M,et al.The Sox gene family and its expression during embyogenes in the teleost fish, medaka(Oryziaslatipes)[J]. Dev Growth Differ,1995,37:379-385.
[13] Ishikawa M,Ito M,Suzuki S.A rainbow trout SRY-type gene expressed inpituitary glands[J]. FEBS Lett,1995,377:37-40.
[14] 常重杰,周荣家,余其兴. 两种泥鳅中PdSox8和PdSox9的RFLP分析[J]. 遗传,2000,22(3):153-156.
[15] Liu Y H,Lou Y D,Qiu G F.PCR amplification of Sox gene in the mud crab Scylla serrata[J]. Journal of Shanghai Fisheries University,2003,12(Suppl):24-27.
[16] 汪桂玲,朱琴,李家乐. 斑节对虾Sox基因HMG盒的PCR扩增及SSCP分析[J]. 水产学报,2005,29(4):478-481.
[17] Matsuda M,Nacahama Y,Shnomya A,et al.DMY is a Y- specific DM-domain gene required formale development in the medaka fish[J]. Nature,2002,417:559-563.
[18] Raymond C S,Shamu C E,Shen M M,et al.Evidence for evolutionary conservation of sex determining genes[J]. Nature,1998,391:691-695.
[19] Nanda I,Kondo M,Hornung U,et al.A duplicated copy of DMRT1 in the sex-determining region of the Y- chromosome of the medaka,Oryzias latipes[J]. Proc Natl Acad Sci USA,2002,99:11778-11783.
[20] Guan G,Kobayashi T,Nagahama Y.Sexually dimorphic expression of two types of DM domain genes in a teleost fish, the Tilapia[J]. Biochem Biophys Res Commun,2000,272(3):662-666.
[21] Marchard O,Goreronn M,D’Cotta H,et al. DMRT1 expression during gonadal differentiation and spermatogenesis in the rainbow trout, Oncorchynchus mykiss[J]. Biochim Biophys Acta,2000,1493(1-2): 180-187.
[22] Matsuda M,Matsuda C,Hamaguchi S,et al.Identification of the sex chromosomes of themedaka, Oryziaslatipes,by fluorescence in situ hybridization[J]. Cytogenet Cell Genet,1998,82(3-4):262-275.
[23] Almeida T L F,Foresti F,Daniel M F,et al. Sex chromosome evolution in fish: the formation of the neo-Y chromosome in Eigenmannia(Gymnotiformes)[J]. Chromosoma,2000,109(3):197-200.
[24] Sakamoto T,Danzmann R G,Gharbi K,et al.A microsatellite linkage map of rainbow trout(Oncorhynchus mykiss)characterized by large sex specific differences in recombination rates[J]. Genetics,2000,155(3):1331-1345.
[25] Nanada I,Schartl M,Epplen J T,et al.Primitive sex chromosomes in poeciliid fishes harbor simple repetitive DNA sequences[J]. J Exp Zool,1993,265(3):301-308.
[26] Kondo M,Nanda I,Hornung U,et al.Absence of the candidaemale sex-determining gene DMRT1b(Y)of medaka from other fish species[J] . Current Biology,2003,13(5):416-420.
[27] Baroiller J F,D’Cotta H. Environment and sex determination in fanned fish[J]. Comparative Biochemistry and Physiology Part C,2001,130(2):399-409.
[28] Kitano T,Takamune K,Kobayashi T,et al.Suppression of P450 aromatese gene expression in sex- reversed males produced by rearing genetically female larvae at a high water temperature during a period of sex differentiation in the Japanese flounder (Para lichthys olivaeus)[J]. J Mol Endocrinol,1999,23(2):167-176.
[29] Kitano T,Takamune K,Nagahama Y,et al.Aromatase inhibitors and 17-methytestosterone cause sex-reversal from genetical female to phenotypic males and suppression of P450 aromatase gene expression in Japanese flounder (Paralichthys olivaceus)[J]. Mol Reprod Dev,2000,56(1):1-5.
[30] Ao A,Erickson R P,Winston R M,et al.Transcription of paternal Y linked genes in the human zygote as early as the prenudeate stage[J]. Zygote,1994,2(4):281-287.
[31] 吴仲庆. 水产生物遗传育种学[M]. 厦门:厦门大学出版社,1991:152-158.
[32] Hattori R S,Murai Y,Oura M,et al.A Y-linked anti-mullerian hormone duplication takes over a critical role in sex determination[J]. Proceedings of the National Academy of Sciences of the USA,2012,109(8): 2955-2959.