LncRNA参与转录后调控作用机制研究进展

doi:10.19640/j.cnki.jtau.2022.02.016

Journal of Tianjin Agricultural University ›› 2022, Vol. 29 ›› Issue (2): 85-87.doi: 10.19640/j.cnki.jtau.2022.02.016

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Research progress on the mechanism of lncRNA involved in post-transcriptional regulation

Yang Xu, Zi Jingjing, Guo Hong, Ding Xiangbin, Liu Xinfeng^{Corresponding Author}, Zhang Linlin^{Corresponding Author}

Tianjin Key Laboratory of Agricultural Animal Breeding and Healthy Husbandry, College of Animal Science and Veterinary Medicine, Tianjin Agricultural University, Tianjin 300392, China

Received:2020-05-18 Online:2022-06-30 Published:2022-07-05

Abstract

Abstract: Long non-coding RNA（lncRNA）is a kind of non-coding RNA with a length longer than 200 nt which widely exists in animal and plant cells. LncRNA can interact with DNA, RNA or proteins to regulate various physiological processes of organisms. In recent years, many newly identified lncRNAs have been reported in the field of large animal genetics and breeding at home and abroad, but there is still a lack of research on the mechanism of lncRNA in the field of animal husbandry. In this article the mechanism of lncRNA-mRNA interaction in post-transcriptional regulation was mainly discussed from the aspects of splicing, transport, translation and degradation of lncRNA regulated mRNAs. The research prospects of lncRNA in animal genetics and breeding has been expected, with a view to provide reference for further development of the function research of lncRNA in large animals.

Key words: lncRNA, mRNA, post-transcriptional regulation

CLC Number:

Yang Xu, Zi Jingjing, Guo Hong, Ding Xiangbin, Liu Xinfeng, Zhang Linlin. Research progress on the mechanism of lncRNA involved in post-transcriptional regulation[J]. Journal of Tianjin Agricultural University, 2022, 29(2): 85-87.

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Research progress on the mechanism of lncRNA involved in post-transcriptional regulation

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