含甘二肽甲酯结构的β-二酮衍生物的合成、除草抑菌活性及构效关系

Journal of Tianjin Agricultural University ›› 2017, Vol. 24 ›› Issue (1): 52-57.

• Researches and Scientific Notes • Previous Articles Next Articles

Synthesis, Herbicidal and Antibacterial Activities, Quantum Chemical Calculation of New β-Diketone Derivatives Containing Glycylglycine Ester

ZHANG Li, LIU Jie, WU Qian, HE Pan-hua, ZHU Hua-ling^{Corresponding Author}, HUANG Zhi-qiang

College of Basic Science, Tianjin Agricultural University, Tianjin 300384, China

Received:2016-06-27 Online:2017-03-31 Published:2019-10-15

Abstract

Abstract: Two new β-diketone derivatives containing glycylglycine methyl ester were synthesized and characterized by IR, UV, ¹H NMR and Elemental analysis. The results of herbicidal activity tests indicated that the inhibition rates of compound B2 at 100 μg/mL to green-bristlegrass were nearly 100%, even higher than the contrast（Glyphosate）. The results of antibacterial activity tests indicated that compound B2 had higher antibacterial ability than compound B1. Theoretical study showed that the existing of thiophen ring and fluorine atoms in compound B2 was the important reason for its better biological activity.

Key words: β-diketone, glycylglycine methyl ester, synthesis, herbicidal and antibacterial activities, quantum chemical calculation

CLC Number:

TQ215

ZHANG Li, LIU Jie, WU Qian, HE Pan-hua, ZHU Hua-ling, HUANG Zhi-qiang. Synthesis, Herbicidal and Antibacterial Activities, Quantum Chemical Calculation of New β-Diketone Derivatives Containing Glycylglycine Ester[J]. Journal of Tianjin Agricultural University, 2017, 24(1): 52-57.

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Synthesis, Herbicidal and Antibacterial Activities, Quantum Chemical Calculation of New β-Diketone Derivatives Containing Glycylglycine Ester

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