石墨烯及其衍生物类药物载体的研究进展

天津农学院学报 ›› 2017, Vol. 24 ›› Issue (1): 88-92.

石墨烯及其衍生物类药物载体的研究进展

王倩, 李晴, 吴庭芳, 郭秋爽, 许艳玲^通信作者

天津农学院基础科学学院,天津 300384

收稿日期:2016-07-04 出版日期:2017-03-31 发布日期:2019-10-15
通讯作者: 许艳玲（1975-）,河北保定人,实验师,博士,研究方向为功能高分子材料。E-mail：369280818@qq.com。
作者简介:王倩（1994-）,山东德州人,本科在读,研究方向为生物制药。E-mail：812231587@qq.com。
基金资助:
国家自然科学基金青年项目“具有开关功能胰岛素载体的制备及其葡萄糖响应性的研究”（21404082）; 天津市大学生创新创业训练计划项目“pH值响应嵌段共聚物/石墨烯复合药物载体的制备及其性能研究”（201510061095）; 国家大学生创新创业训练计划项目“温度响应性氧化石墨烯纳米药物控释体的制备及释药性研究”（201610061078）

Research Progress of Graphene and Its Derivatives Used as Drug Carrier

WANG Qian, LI Qing, WU Ting-fang, GUO Qiu-shuang, XU Yan-ling^{Corresponding Author}

College of Basic Science, Tianjin Agricultural University, Tianjin 300384, China

Received:2016-07-04 Online:2017-03-31 Published:2019-10-15

摘要/Abstract

摘要： 石墨烯作为碳材料的新成员,从2004 年被发现至今,已引起了科学家的极大兴趣。石墨烯是处于蜂窝状晶体点阵上的碳原子以sp²杂化链接形成的单原子层二维晶体,具有许多独特的理化性质,已成为当前研究的热点之一。石墨烯及其衍生物在载药方面的应用正处在探索阶段,当前,根据实际需求对石墨烯及其衍生物进行药物载体方面的研究是一项极富挑战性的工作。本文重点介绍了石墨烯尤其是氧化石墨烯应用于药物载体方面的最新研究进展,指出了目前石墨烯类材料在药物载体应用中存在的问题,并对其发展进行了展望。

关键词: 石墨烯, 氧化石墨烯, 药物载体

Abstract: As the new member of the carbon materials, graphene has brought up great interest of scientists since it was found at 2004. Graphene is a kind of two-dimensional crystal of a single atomic layer which has a honeycomb crystal lattice of carbon atoms in a sp² hybrid link formation, exhibits many unique physical and chemical properties and excellent performance due to the unique structure. The current studies on graphene and its derivatives mainly concentrated on the field of the physics, chemistry and materials science. The application of graphene and its derivatives on medical materials and drug delivery is still in exploring stage and regarded as a challenging work. In this paper, the latest research progress in the application of graphene and its derivatives in drug carrier are mainly introduced. The existing problems in the application of graphene materials in drug carriers are also pointed out and the possible development is prospected.

Key words: graphene, oxide graphene, drug carrier

中图分类号:

O613.71

王倩, 李晴, 吴庭芳, 郭秋爽, 许艳玲. 石墨烯及其衍生物类药物载体的研究进展[J]. 天津农学院学报, 2017, 24(1): 88-92.

WANG Qian, LI Qing, WU Ting-fang, GUO Qiu-shuang, XU Yan-ling. Research Progress of Graphene and Its Derivatives Used as Drug Carrier[J]. Journal of Tianjin Agricultural University, 2017, 24(1): 88-92.

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链接本文: http://xuebao.tjau.edu.cn/CN/

http://xuebao.tjau.edu.cn/CN/Y2017/V24/I1/88

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