禽TCR谱系分析的研究进展

Journal of Tianjin Agricultural University ›› 2014, Vol. 21 ›› Issue (3): 44-48.

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Research Progress of Avian TCR Repertoire Analysis

REN Chao¹, LIU Xian-yong², CUI Li³

1. College of Animal Science and Veterinary Medicine, Tianjin Agricultural University, Tianjin 300384, China;
2. College of Veterinary Medicine, China Agricultural University, Beijing 100094, China;
3. Xiqing District Animal Health Authority of Tianjin City, Tianjin 300380, China

Received:2014-02-20 Online:2014-09-20 Published:2019-10-21

Abstract

Abstract: Avian T cell can convert the external signal into internal signal via TCR, which can stimulate T cell proliferation and differentiation and play an important role in immune function. TCR clones of the body can be fully shown and evaluate the immune functions comprehensively by TCR repertoire analysis. The technologies of TCR repertoire analysis have been extensively applied to the fields of pathogen infection, tumor, autoimmune disease, and so on. More useful research resources about the biological characteristics of pathogens, diagnosing, preventing and controlling the relevant diseases can be provided by exploring the changes of TCR clones in avian pathogen infection and tumor diseases with using the technologies of TCR repertoire analysis.

Key words: avian TCR, repertoire analysis, T cell clone, immunodominant, diversity

CLC Number:

S857.4

REN Chao, LIU Xian-yong, CUI Li. Research Progress of Avian TCR Repertoire Analysis[J]. Journal of Tianjin Agricultural University, 2014, 21(3): 44-48.

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Research Progress of Avian TCR Repertoire Analysis

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