猪链球菌黏附机制及其相关毒力因子研究进展

天津农学院学报 ›› 2017, Vol. 24 ›› Issue (4): 77-80.

猪链球菌黏附机制及其相关毒力因子研究进展

付超, 刘梦月, 赵瑞利^通信作者, 胡烨, 马吉飞, 崔君

天津农学院动物科学与动物医学学院,天津 300384

收稿日期:2017-08-15 出版日期:2017-12-31 发布日期:2019-10-15
通讯作者: 赵瑞利（1979-）,女,河北石家庄人,副教授,博士,研究方向为分子病原细菌学。E-mail：zhaoruili1109@126.com。
作者简介:付超（1990-）,男,甘肃庆阳人,硕士在读,研究方向为动物病原学与免疫学。E-mail：18393813292@163.com。
基金资助:
天津市应用基础与前沿技术研究计划一般项目“新牛蛙抗菌肽RGD—嵌合体的分子设计及其靶向抗肿瘤研究”（14JCYBJC30000）; 天津市大学生创新创业训练计划项目“天津地区警犬点滴复膜酵母菌的分子流行病学调查及致病性研究”（201610061004）; 天津农学院科技发展基金计划“新牛蛙抗菌肽pGAP启动子组成型表达载体的构建及表达”（2012N18）; 天津市农委资助项目“天津市生猪产业技术体系创新团队—细菌病岗位”（ITTPRS2017004）

Research Advances of Adhesion Mechanism and Pathogenic Factor in Streptococcus suis

FU Chao, LIU Meng-yue, ZHAO Rui-li^{Corresponding Author}, HU Ye, MA Ji-fei, CUI Jun

College of Animal Science and Veterinary Medicine, Tianjin Agricultural University, Tianjin 300384, China

Received:2017-08-15 Online:2017-12-31 Published:2019-10-15

摘要/Abstract

摘要： 猪链球菌（Streptococcus suis, S. suis）是一种重要的人兽共患病原菌,流行范围广、致病能力强,可引起猪的一系列疾病,同时也对人的健康构成严重威胁。近年来,S. suis感染人和动物的报道日益增加,逐渐得到人们的广泛关注。S. suis感染发病的第一步是对宿主的黏附,研究细菌黏附及毒力因子（如plcR等）已成为热点。本文主要通过对S. suis黏附、毒力因子等进行综述,总结主要黏附机制和相关毒力因子,旨在为S. suis的进一步研究奠定基础,为防控S. suis感染提供参考。

关键词: 猪链球菌, 黏附机制, 毒力因子

Abstract: Streptococcus suis（S. suis）is a momentous zoonotic pathogen, with wide range of epidemic and strong ability of pathogenic, which could cause a series of swine disease as well as pose a serious threat to human health. In recent years, some reports about S. suis infected people and animals are increasing, and it attracted people’s widespread attention gradually. The first step of the pathogenesis of S. suis infection is the adhesion to host, the studies onthe adhesion and virulence factors （such asplcR, etc.）of the bacterium have become a research hotspot. In the review, the adhesion and virulence factors of S. suis were mainly overviewed, meanwhile, the main adherentmechanism and involved virulence factors were summarized, the aim of it is to lay a foundation for the further study of S. suis, and to provide a reference for prevention and control of S. suis infection.

Key words: S. suis, adhesion mechanism, virulence factor

中图分类号:

S852.611

付超, 刘梦月, 赵瑞利, 胡烨, 马吉飞, 崔君. 猪链球菌黏附机制及其相关毒力因子研究进展[J]. 天津农学院学报, 2017, 24(4): 77-80.

FU Chao, LIU Meng-yue, ZHAO Rui-li, HU Ye, MA Ji-fei, CUI Jun. Research Advances of Adhesion Mechanism and Pathogenic Factor in Streptococcus suis[J]. Journal of Tianjin Agricultural University, 2017, 24(4): 77-80.

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链接本文: http://xuebao.tjau.edu.cn/CN/

http://xuebao.tjau.edu.cn/CN/Y2017/V24/I4/77

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